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Oxidative Stress and Aging
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VOLUME: 11 ISSUE: 3
P: 31-35
September 2020

Oxidative Stress and Aging

Dermatoz 2020;11(3):31-35
DOI: 10.4274/dermatoz.galenos.2021.68077
Ali Tanakol
Tuğba Kevser Uzunçakmak
Zekayi Kutlubay
1. İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi, Deri ve Zührevi Hastalıklar Anabilim Dalı, İstanbul, Türkiye
No information available.
No information available
Received Date: 18.12.2020
Accepted Date: 08.01.2021
Publish Date: 16.03.2021
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ABSTRACT

Ageing is characterized by many changes in the organism and very complex difficult process to understand. Although this process is tried to be explained with various theories, these approaches should not be considered separately from each other. The free radical theory put forward by Harman in 1956 and later the arrangement of this theory centered on the mitochondria were accepted. Antioxidant defense systems have been shown to work in balance with reactive oxygen products against the damage caused by reactive oxygen products at pathological levels. It has been shown that oxidative stress arises as a result of the disturbance of this balance. It has been shown that various diseases other than aging due to oxidative stress occur. It has been reported that reactive oxygen products formed in physiological doses can protect the organism against various diseases. Today, oxidative damage in the organism can be measured at certain levels and this damage mechanism can be shown in some diseases.

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