ABSTRACT
Glomagiomatosis is an arteriovenous malformation of the skin that occurs as asymptomatic multiple pink to blue nodules or plaques. Multiple occurrences of lesions are extremely rare and represent 10% of all cases. Familial cases are caused by mutations in the glomulin gene. In contrast to glomus tumors, which generally prefer subungual regions in young adults, glomagiomatosis often manifests itself with multiple lesions in various parts of the body in children or adolescence. In this article, we present a 24-year-old male case diagnosed with familial diffuse cutaneous glomagiomatosis.
Keywords:
Glomus, arteriovenous malformation, vascular lesion
References
1
Fitzhugh VA, Beebe KS, Wenokor C, Blacksin M. Glomangiomatosis: a case report. Skeletal Radiol 2017; 46: 1427-1433.
2
Calduch L, Monteagudo C, Martínez E, et al. Familial generalized multiple glomangiomyoma: report of a new family, with immunohistochemical and ultrastructural studies and review of the literature. Pediatr Dermatol 2002; 19: 402-408.
3
Conant MA, Wiesenfeld SL. Multiple glomus tumors of the skin. Arch Dermatol 1971; 103: 481-485.
4
Schopp JG, Sra KK, Wilkerson MG. Glomangioma: a case report and review of the literature. Cutis 2009; 83: 24-27.
5
Aiba M, Hirayama A, Kuramochi S. Glomangiosarcoma in a glomus tumor. An immunohistochemical and ultrastructural study. Cancer 1988; 61: 1467-1471.
6
Barnes L, Estes SA. Laser treatment of hereditary multiple glomus tumors. J Dermatol Surg Oncol 1986; 12: 912-915.