ABSTRACT

Epidermolysis bullosa (EB) is a genetic disease characterized by blisters on skin and mucous membranes as a result of mechanical fragility. The eye involvement are common and vary in epidermolysis bullosa subtypes. Eye complications are the most serious in dystrophic and junctional types. Junctional type of EB patient with recurrent corneal erosion and resistant oral mucosal lesions was treated with autologous serum (OS). Additionally, OS could be effective in the treatment of oral mucosal lesions in EB patients.